Polymer Based Solubility Enhancement Excipients Market to grow at a CAGR of 16.84% during 2024-2028
The Polymer Based Solubility Enhancement Excipients Market is expected to grow at a CAGR of 16.84% during 2023 and 2028. During this period, the market is also expected to show a growth of USD 3907.24 million. In the pharmaceutical industry, there has been a notable shift from captive API manufacturing towards outsourcing to Contract Manufacturing Organizations (CMOs) and other drug manufacturing entities. Initially, outsourcing was limited to early-stage API intermediates; however, it has since expanded to advanced intermediates and final dosage forms. Factors influencing this decision include industry trends, the high cost of acquiring new, in-house technologies, and the availability of internal capacity. The outsourcing of Polymer Based Solubility Enhancement Excipients is a prime example of this trend, as companies seek to optimize their resources and focus on their core competencies.
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Technavio analysts predict that the Copovidone subsegment will lead the Type segment during 2024 and 2028 Copovidone, a white- or yellowish-white spray-dried powder, is a crucial polymer-based excipient in the pharmaceutical industry. Comprised of 1-vinyl-2-pyrrolidone and vinyl acetate in a 3:2 weight ratio, it functions as a versatile binding agent, granulating agent, retarding agent, and film-forming agent. Its primary application lies in enhancing the solubility and bioavailability of poorly soluble active pharmaceutical ingredients (APIs). Through the creation of spray-dried or melt-extruded solid dispersions, copovidone significantly increases the efficacy of pharmaceutical formulations, making it an indispensable component in the pharmaceutical industry.
Here are the various ways based on which the market is segmented:
There are several factors that are causing the market to flourish rising demand for polymer excipients
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The Polymer-Based Solubility Enhancement Excipients Market has gained significant attention in the pharmaceutical industry due to the increasing number of poorly water-soluble Active Pharmaceutical Ingredients (APIs). These excipients, such as crystallization-inhibiting polymers, amphiphilic compounds, and biodegradable and biocompatible polymers, play a crucial role in enhancing the solubility of hydrophobic APIs under various pH conditions. Dissolution tests are essential in evaluating the effectiveness of these excipients. The use of excipient technology, including polymeric micelle-based formulations, amorphous solid dispersions, inclusion complexes, encapsulation, API physical modification, and API chemical modification, has been instrumental in improving the bioavailability of New Chemical Entities (NCEs) and addressing solubility challenges. Excipients like spray drying, pH-sensitive polymers, and hydrophilic polymers are used to improve the dissolution rate and drug loading of parenteral products. Good Manufacturing Practices (GMP) ensure the quality and safety of these formulations. The market for polymer-based solubility enhancement excipients is expected to grow as pharmaceutical innovation continues to focus on addressing the solubility challenges of hydrophobic APIs and improving the bioavailability of NCEs. The use of these excipients in various dosage forms, including tablets, capsules, and injectables, will drive market growth.
According to Technavio, the global polymer based solubility enhancement excipients market is a significant segment of the expansive specialty chemicals industry. The specialty chemicals market encompasses businesses specializing in high-value-add chemicals used in the production of a diverse range of products, such as fine chemicals, additives, advanced polymers, adhesives, sealants, specialty paints, pigments, and coatings. Technavio's market analysis calculates the size of the global specialty chemicals market by aggregating the revenues generated by manufacturers of high-value-added chemicals involved in the production of various items. Factors propelling the growth of the specialty chemicals market include the increasing preference for specialty adhesives and sealants, which is a burgeoning trend in numerous industries.
The Polymer Based Solubility Enhancement Excipients Market is experiencing significant growth, fueled by the rising demand for polymer excipients. Industries are leveraging the products belonging to the market for customer engagement, transactional notifications, and promotional offers.
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