Authored By: Sarah
15 Jul 2024

 Bioreactors Market Size to grow by USD 2231.3 million between 2024-2028

According to a research report “ Bioreactors Market” by End-user (Biopharmaceutical companies, Research institutes, Contract research organizations) Type (Automated, Manual) Geography (North America, Europe, Asia, Rest of World (ROW))- Global Forecast to 2028 published by Technavio, the market size is estimated to grow by USD 2231.3 million, at a CAGR of  6.99% during the forecast period. The global bioreactors market has witnessed a surge in demand for single-use bioreactors due to their numerous advantages. Compared to traditional stainless steel bioreactors, single-use bioreactors offer simpler setup processes for continuous processing. For instance, GE Healthcare's ReadyToProcess WAVE 25 Rocker features disposable cell bag chambers with integrated perfusion filters, enabling small-scale continuous perfusion cultures to be established swiftly and without the complications of connecting external perfusion devices. Moreover, a single-use bioreactor previously employed in fed-batch manufacturing can be effortlessly adapted to cater to the needs of continuous processing operations.

Browse market data tables, figures, and in-depth TOC on “Bioreactors Market” by End-user (Biopharmaceutical companies, Research institutes, Contract research organizations) Type (Automated, Manual) Geography (North America, Europe, Asia, Rest of World (ROW)) Global Forecast to 2028. Download Free Sample


By End-user, the Biopharmaceutical companies segment is projected to dominate the market size in 2024

In the realm of biotechnology and pharmaceuticals, automated bioreactors have emerged as essential tools for the cultivation of microorganisms, mammalian cells, and other biological entities. The burgeoning demand for these advanced systems is fueled by the biopharmaceutical sector, which heavily relies on bioreactors for the large-scale production of therapeutic proteins, monoclonal antibodies, vaccines, and other biologics. Automated bioreactors offer numerous advantages, including consistent and controlled production processes, higher product yields, and improved product quality. By automating the bioreactor systems, we can precisely manage critical parameters such as temperature, pH, dissolved oxygen, and nutrient supply. This results in optimized growth conditions, minimizing variability, and enhancing overall process efficiency. The ability to maintain optimal conditions leads to increased productivity and higher-quality outputs, making automated bioreactors an indispensable investment for businesses in the life sciences industry.

By Type, Automated  segment is expected to hold the largest market size for the year 2024

In today's healthcare landscape, pharmaceutical and biotechnology firms are under immense pressure to produce high-quality, regulatorily compliant drugs and therapeutic treatments due to the rising incidence of chronic diseases worldwide. Bioreactors play a pivotal role in this process, particularly during the drug discovery phase. These advanced systems facilitate the screening and development of clinically relevant compounds through various applications, including media and buffer preparation, crossflow filtration, viral clearance, cell harvesting, and virus inactivation. During cell cultivation, bioreactors enable precise control over critical parameters such as nutrient medium composition, dissolved oxygen saturation, pH, mixing efficiency, and temperature, ensuring optimal cell growth and product yield.

North America is forecasted to hold the largest market size by region in 2024

The North American bioreactors market is experiencing robust growth due to substantial investments in healthcare research and testing in the United States. The region's strong distribution networks in countries like the US and Canada, coupled with the increasing focus of biopharmaceutical companies on drug discovery and development, are primary growth drivers. The US dominates the market, with key players such as Danaher, Thermo Fisher Scientific, Merck KGaA, and GE Healthcare headquartered there. These prominent vendors' presence significantly enhances the supply chain's efficiency, ensuring timely availability of bioreactors for end-users and boosting adoption rates.

The Bioreactors Market growth and forecasting report also includes detailed analyses of the competitive landscape of the market growth and forecasting and information about 20 market companies, including:

  • Automated Engineering Services Inc.
  • Bioengineering AG
  • BPC Instruments AB
  • Cell Culture Co. LLC
  • Danaher Corp.
  • Distek Inc.
  • Donaldson Co. Inc.
  • Eppendorf SE
  • Getinge AB
  • Infors AG
  • LAMBDA CZ sro
  • Merck KGaA
  • PBS Biotech Inc.
  • Pierre Guerin SA
  • Sartorius AG
  • Solida Biotech GmBH
  • Thermo Fisher Scientific Inc.
  • Zellwerk GmbH
  • ZETA
  • 3D Biotek LLC

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Research Analysis Overview

The Bioreactors Market is witnessing significant growth due to the increasing demand for personalized medicines, preventive vaccines, and biological interventions for chronic diseases such as cardiovascular diseases, cancer, and diabetes. Bioreactors are essential bioprocessing equipment used to create ideal conditions for the growth of microorganisms like yeast, which are used in the production of various biologics. Key factors driving the market include the need for precise control of critical parameters such as Dissolved oxygen, pH, and Temperature to ensure therapeutic efficacy. The market for bioreactors is diverse, catering to various disease indications, including cancer, diabetes, and cardiovascular diseases. Clinical trials for new biological interventions require stringent safety profiles and regulatory compliance. Bioreactors come in various volumes, control types, and materials, including stainless steel and hybrid technologies. Leachable and extractable components are a regulatory concern, and biopharmaceutical companies are investing in advanced technologies to address these issues. The market for bioreactors is expected to grow significantly due to the increasing demand for biologics in the treatment of chronic diseases. The use of bioreactors in the production of personalized medicines and preventive vaccines is also expected to fuel market growth. However, the high cost of bioreactors and the need for specialized expertise in their operation are potential challenges.

Market Research Overview

The Bioreactors Market is a significant segment of the biotechnology sector, focusing on cost-effective production of biologicals, including animal cells, bacteria, yeast, and other microbial cell populations. Bioreactors are essential for producing personalized medicines, preventive vaccines, and addressing chronic diseases such as cardiovascular diseases, cancer, and diabetes. The market includes various types of bioreactors, including modular, continuous mode, and large-scale bioreactors, as well as micro-mini bioreactors with different dimensions and volumes. Key players in the market include Sartorius and Repligen, Culture Biosciences, PBS Biotech, and Footprint. These companies offer efficient, user-friendly bioreactors with advanced technologies like Vertical wheel technology, Perfusion, and Rocker. Bioreactors are used for producing various biologicals, including bispecific antibodies, monoclonal antibodies, antibody production, enzymes, and recombinant proteins. The vaccine segment and mammalian cells segment are expected to dominate the market due to the increasing demand for vaccines and personalized medicines. However, challenges such as raw materials, bottlenecks, leachables and extractables, and troubleshooting remain. Bioreactor systems are also used for producing 3D tissue, fusion proteins, and specialized biologics. The bioprocessing equipment market is expected to grow as bioreactors move towards clinical trials and biological interventions for disease indications with ideal safety profiles and therapeutic efficacy. Biomanufacturing facilities and system integrators play a crucial role in the biopharmaceutical industry, requiring skilled labor, mass flow controllers, surface cleaning, temperature monitoring, and automation complexity. Regulatory concerns and the use of materials like stainless steel, plastic, and hybrid technologies are also significant factors in the market.


Technavio Research
Jesse Maida
Media & Marketing Executive
US: +1 844 364 1100
UK: +44 203 893 3200

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