increasing incidence of cancer boosts demand for novel diagnostics is driving the Aptamers Market
Technavio analyzes that the Aptamers Market is expected to grow at a CAGR of 52.5% during 2023 and 2028. During this period, the market is also expected to show a growth of USD 4195.1 million.There are various factors that contribute to the growth of the market. The rising prevalence of cancer globally is fueling the demand for advanced diagnostic tools. Aptamers, a class of nucleic acid molecules, are gaining significant attention in the diagnostics market due to their high specificity and sensitivity. These molecules can be engineered to bind to specific targets, making them ideal for the development of novel diagnostic tests. The aptamer market is expected to experience robust growth in the coming years, driven by the increasing need for early and accurate cancer diagnosis.
In the dynamic and innovative landscape of the aptamers market, the therapeutics development segment emerged as the market leader in 2023, driven by an escalating number of clinical trials assessing aptamers for novel therapies and strategic collaborations between aptamer vendors and prominent pharmaceutical and biotechnology corporations. For therapeutic applications, aptamers undergo truncation, sugar modification, and termini capping to minimize synthesis costs and enhance nuclease resistance. The first approved aptamer for therapeutic use was pegaptanib sodium, authorized by the US FDA in 2004 for age-related macular degeneration treatment. However, the therapeutic application of aptamers is encumbered by their vulnerability to ubiquitous serum nucleases, swift renal filtration, and insufficient in vivo binding affinity for their targets. In the diagnostic kits segment, SELEX technology is employed for aptamer discovery, while aptamers targeting SARS-COV-2, biomarkers for cancer, and cardiovascular disease (CVD) are gaining significant attention. Aptamex, a second-generation diagnostic kit, is a notable example of aptamer-based diagnostic technology.
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Aptamers Market Segmentation
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Aptamers, specifically oligonucleotide aptamers and nucleic acid-based aptamers like DNA aptamers, are small non-antibody molecules that bind to target proteins with high affinity and specificity. These biotechnological innovations offer advantages over antibodies for chronic disease diagnosis and therapeutics. SELEX (Systematic Evolution of Ligands by Exponential Enrichment) and MARAS (Multiple Affinity Selection) techniques are used to discover aptamers. Aptamers can be utilized in diagnostic procedures and tests for biomarkers such as cortisol, SARS-COV-2, and others. Graphene-based sensing systems enhance aptamer detection. Aptamers have small molecular size, low immunogenicity, and can target cells. They are valuable in drug delivery, therapeutics, and diagnostic kits. Their high binding affinity makes them suitable for precision and personalized medicine, therapeutic development, and drug discovery. Aptamers can also act as therapeutic agents and peptide aptamers are under exploration. SELEX technology is employed in the discovery of aptamers for various applications including diagnostic tests and therapeutics. Pharmaceutical companies like Aptamex are focusing on the development of aptamers for diagnostic applications and therapeutic development.
The global life sciences tools and services market encompasses organizations involved in the research and development (R&D) of a range of product categories, including capital equipment, instruments, accessories, and consumables. These tools are utilized in the pharmaceutical and biotechnology industries, as well as in laboratory diagnosis of chronic diseases. Additionally, the market covers life sciences-related services such as contract research, manufacturing, and sales. According to Technavio, the healthcare industry's total revenue is determined by the earnings of equipment, supply, pharmaceutical, biotechnology, and life science tools and services manufacturers. Factors driving market growth include an aging population, with the global population aged 60 and above projected to increase substantially, and the ongoing development of advanced diagnostic procedures and tests for therapeutic applications, such as cortisol detection using graphene-based sensing systems in biotechnology.. Industries are leveraging the products belonging to the market for customer engagement, transactional notifications, and promotional offers.
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